miRNAs - Latest research and news | Nature
WEB6 days ago · Mechanistically, microRNA (miRNA) cargoes within these sEVs alleviated age-related dysfunction by promoting the expression of PGC1α and enhancing mitochondrial energy metabolism.
microRNAs in action: biogenesis, function and regulation
WEBJun 28, 2023 · In this Review, the authors describe how the application of new technologies to the microRNA (miRNA) field has yielded key insights into miRNA biology.
MicroRNA amplification and detection technologies: opportunities …
WEBDec 12, 2018 · Metcalf GAD, Shibakawa A, Pate H, et al. Amplification-free detection of circulating microRNA biomarkers from body fluids based on fluorogenic oligonucleotide-templated reaction between engineered ...
MicroRNA therapeutics: towards a new era for the management of …
WEBFeb 17, 2017 · Overview of microRNA (miRNA) biogenesis, highlighting key mutations and deregulated factors that play a part in diseases related to alterations in miRNAs. miRNAs are produced in a tightly ...
miRNA in immune cells - Latest research and news | Nature
WEBSep 6, 2024 · New findings show that microRNA-mediated control of target-gene expression is also dependent on the cellular context.
MicroRNA profiling: approaches and considerations - Nature
WEBApr 18, 2012 · This Review describes the methods that are available for microRNA profiling and considerations for choosing among analytical options.
MicroRNAs: circulating biomarkers for the early detection of ...
WEBJun 5, 2024 · These reasons, combined with technological advances in biosensor and machine-learning development, have led to heightened interest in the area of clinically pertinent microRNA (miRNA) biomarkers ...
MicroRNA sponges: competitive inhibitors of small RNAs in
WEBAug 12, 2007 · We made decoy targets for several microRNA seed families, named them 'microRNA sponges', and tested their ability to derepress microRNA targets in mammalian cells.
MicroRNA: trends in clinical trials of cancer diagnosis and therapy ...
WEBJul 10, 2023 · As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in cancer development.
Regulation of microRNA function in animals - Nature
WEBAug 14, 2018 · Ser387 phosphorylation increases microRNA (miRNA) activity by stimulating the assembly of miRNA-induced silencing complexes and reduces translocation of Ago2 to multivesicular endosomes and ...